Lamivudine treatment for children with interferon refractory chronic hepatitis B
نویسندگان
چکیده
منابع مشابه
Comparison of interferon monotherapy with interferon-lamivudine combination treatment in children with chronic hepatitis B.
AIM To compare interferon monotherapy with combination treatment using interferon and lamivudine in children with chronic hepatitis B. METHODS Data from 65 children who had received either interferon-alpha (5 MU/m2 subcutaneous thrice a week for 6 months; n=35; Group 1) or this dose of interferon-alpha for 6 months with oral lamivudine for one year (4 mg/Kg/day, maximum 100 mg/day; n=30; Grou...
متن کاملEffect of Interferon-α and Combined Interferon-α with Lamivudine Treatment on Anthropometric Measurements in Children with Chronic Hepatitis B.
ated in each group, TST and SST Z-scores of HBeAg-positive patients were significantly higher than those in anti-HBe positive patients in group 1 ( p < 0.05). No statistically significant differences were observed in the other Z-scores ( p > 0.05). When HBeAg-positive patients and antiHBe-positive patients were compared in group 2, TST, SST, MAC, and MAMA Z-scores were not found to be statistic...
متن کاملLamivudine Therapy for Korean Children with Chronic Hepatitis B
PURPOSE Lamivudine is known to be very effective in suppressing hepatitis B virus replication and virus induced necroinflammation. The aim of this study was to evaluate lamivudine therapy efficacy, predictive factors, breakthrough, prevalence of YMDD mutation, and relapse rate in Korean children with chronic hepatitis B. MATERIALS AND METHODS Between August 1999 and February 2005, 60 children...
متن کاملTreatment of Chronic Hepatitis B with Tenofovir
Background:Tenofovir is among the first-line treatments for chronic hepatitis B (CHB) virus infection. We evaluated the efficacy of Tenofovir in the treatment of Iranian adult patients with CHB. Methods: In a retrospective study, we evaluated 154 HBsAg positive patients referred to Sadoughi hospital in Yazd-Iran for treatment ...
متن کاملClinical trial of lamivudine in children with chronic hepatitis B.
BACKGROUND Lamivudine therapy is effective for chronic hepatitis B infection in adults. We evaluated the efficacy and tolerability of lamivudine as a treatment for chronic infection with hepatitis B virus (HBV) in children. METHODS Children with chronic hepatitis B were randomly assigned in a 2:1 ratio to receive either oral lamivudine (3 mg per kilogram of body weight; maximum, 100 mg) or pl...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2000
ISSN: 0270-9139
DOI: 10.1002/hep.510310246